Title:
SUBSTITUTED N-PHENYLPYRIMIDIN-2-AMINE ANALOGS AS INHIBITORS OF THE AXL KINASE
Document Type and Number:
Japanese Patent JP2017075188
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide substituted N-phenylpyrimidin-2-amine analogs as inhibitors of the AXL kinase.SOLUTION: In one aspect, the invention relates to substituted N-phenylpyrimidin-2-amine analogs, derivatives thereof, and related compounds, which are useful as inhibitors of Axl kinase; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds and compositions for treating disorders associated with dysfunction of the Axl kinase. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.SELECTED DRAWING: None
Inventors:
DAVID J BEARSS
HARIPRASAD VANKAYALAPATI
ALEXIS MOLLARD
STEVEN L WARNER
SUNIL SHARMA
HARIPRASAD VANKAYALAPATI
ALEXIS MOLLARD
STEVEN L WARNER
SUNIL SHARMA
Application Number:
JP2017018561A
Publication Date:
April 20, 2017
Filing Date:
February 03, 2017
Export Citation:
Assignee:
UNIV UTAH RES FOUND
International Classes:
C07D239/42; A61K31/506; A61K31/5377; A61K45/00; A61P35/00; A61P35/02; A61P43/00; C07D401/12
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto