Title:
置換ピリジン化合物
Document Type and Number:
Japanese Patent JP5739426
Kind Code:
B2
Abstract:
The present invention provides a substituted pyridine compound or a pharmacologically acceptable salt thereof which has excellent CETP inhibition activity and is useful as a medicament. The present invention provides a compound represented by a general formula (I),
wherein R 1 is H, optionally substituted alkyl, OH, optionally substituted alkoxy, alkylsulfonyl, optionally substituted amino, carboxy, optionally substituted carbonyl, CN, halogeno, optionally substituted phenyl, optionally substituted aromatic heterocyclyl, optionally substituted saturated heterocyclyl, optionally substituted saturated heterocyclyloxy or optionally substituted saturated heterocyclylcarbonyl, etc., and the like.
Inventors:
Masahiko Hagiwara
Noriaki Iwase
Katsunori Takada
Kikuchi Osamu
Tsuboike Issei
Hiroyuki Setoguchi
Kenji Yoneda
Hidetoshi Sunamoto
Yukiharu Ito
Takesh Nakamura
Hideki Futaki
Nao Terasaka
Akiko Shima
Noriaki Iwase
Katsunori Takada
Kikuchi Osamu
Tsuboike Issei
Hiroyuki Setoguchi
Kenji Yoneda
Hidetoshi Sunamoto
Yukiharu Ito
Takesh Nakamura
Hideki Futaki
Nao Terasaka
Akiko Shima
Application Number:
JP2012523924A
Publication Date:
June 24, 2015
Filing Date:
July 08, 2011
Export Citation:
Assignee:
Ube Industries,Ltd.
Daiichi Sankyo Co., Ltd.
Daiichi Sankyo Co., Ltd.
International Classes:
C07D401/14; A61K31/506; A61K31/5377; A61K31/541; A61P3/04; A61P3/06; A61P9/10; A61P43/00
Domestic Patent References:
| JP2008524145A | 2008-07-10 | |||
| JP2001516757A | 2001-10-02 | |||
| JP2008524145A | 2008-07-10 | |||
| JP2001516757A | 2001-10-02 |
Foreign References:
| WO1999041237A1 | 1999-08-19 | |||
| WO2008156715A1 | 2008-12-24 | |||
| WO1999041237A1 | 1999-08-19 | |||
| WO2008156715A1 | 2008-12-24 |
Attorney, Agent or Firm:
Kimiki Ishibashi
Imamura Mayu
Toshiyasu Takemoto
Imamura Mayu
Toshiyasu Takemoto