Title:
置換1-アミノアルキルラクタム及びムスカリンレセプターアンタゴニストとしてのそれらの使用
Document Type and Number:
Japanese Patent JP3955211
Kind Code:
B2
Abstract:
This invention relates to compounds which are generally muscarinic M2/M3 receptor antagonists and which are represented by Formula I:wherein X, Y, and Z are O, S, or NR<4>, and the other substituents are as defined in the specification; and prodrugs, individual isomers, racemic or non-racemic mixtures of isomers, and pharmaceutically acceptable salts or solvates thereof. The invention further relates to pharmaceutical compositions containing such compounds and methods for their use as therapeutic agents.
Inventors:
Madera, Anne Marie
Russell Stephen, Stabler
Weikart, Robert James
Russell Stephen, Stabler
Weikart, Robert James
Application Number:
JP2001586271A
Publication Date:
August 08, 2007
Filing Date:
May 17, 2001
Export Citation:
Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
A61K31/33; C07D241/08; A61K31/395; A61K31/495; A61K31/496; A61K31/535; A61K31/5377; A61K31/55; A61K31/551; A61K31/553; A61P1/00; A61P1/06; A61P11/00; A61P11/06; A61P13/02; A61P13/06; A61P15/00; A61P21/00; A61P21/02; A61P43/00; C07D207/27; C07D211/76; C07D223/10; C07D225/02; C07D239/10; C07D243/04; C07D243/08; C07D265/10; C07D267/06; C07D267/10; C07D267/22; C07D279/06; C07D401/06; C07D401/12; C07D403/06; C07D403/12; C07D405/06; C07D405/12; C07D405/14; C07D409/06; C07D409/12; C07D409/14; C07D411/12; C07D413/06; C07D413/12; C07D413/14; C07D417/06; C07D417/12; C07D417/14; C07D207/26
Domestic Patent References:
| JP60016976A |
Foreign References:
| WO1999043657A1 | ||||
| WO1999005095A1 |
Attorney, Agent or Firm:
Hajime Tsukuni
Fumio Shinoda
Fumio Shinoda