Title:
ポリ(ADP-リボース)ポリメラーゼ阻害剤としての置換6-シクロヘキシルアルキル置換2-キノリノンおよび2-キノキサリノン
Document Type and Number:
Japanese Patent JP4948178
Kind Code:
B2
Abstract:
The present invention provides compounds of formula (I), their use as PARP inhibitors as well as pharmaceutical compositions comprising said compounds of formula (I) wherein n, s, R1, R2, R3, Q, X and Y have defined meanings.
Inventors:
Maville, Dominique Jean-Pierre
Ban Deyun, Jacobs Alhuons Sus Josef
Somer, Maria Victorina Francisca
Wooters, Walter Budewin Leopold
Ban Deyun, Jacobs Alhuons Sus Josef
Somer, Maria Victorina Francisca
Wooters, Walter Budewin Leopold
Application Number:
JP2006543409A
Publication Date:
June 06, 2012
Filing Date:
November 18, 2004
Export Citation:
Assignee:
JANSSEN PHARMACEUTICA NAAMLOZE VENNOOTSCHAP
International Classes:
C07D215/22; A61K31/4704; A61K31/4725; A61K31/496; A61K31/498; A61K31/5377; A61P3/08; A61P9/10; A61P17/16; A61P19/02; A61P19/10; A61P21/00; A61P25/00; A61P25/08; A61P25/14; A61P25/16; A61P25/18; A61P25/28; A61P29/00; A61P31/04; A61P31/18; A61P35/00; A61P37/04; A61P39/02; A61P43/00; C07D215/227; C07D241/44; C07D401/06; C07D401/14; C07D409/14; C07D491/10; C07D491/107
Domestic Patent References:
| JP2007513101A |
Foreign References:
| EP0371564A1 | ||||
| WO2002028837A1 | ||||
| WO2003082350A1 |
Attorney, Agent or Firm:
Patent business corporation Odashima patent office