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Title:
置換シクロヘキサン誘導体
Document Type and Number:
Japanese Patent JP2005513127
Kind Code:
A
Abstract:
The present invention provides compounds of formula (I) wherein A1, A2, A3, A4, A5, A6, A7, A8, A9, A10, U, V, W, m, n and p are as indicated in the specification, and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with 2,3-oxidosqualene-lanosterol cyclase such as hypercholesterolemia and hyperlipemia.

Inventors:
Ackerman, Jean
Shrimp, Johannes
Henrietta, Damelow
Iltu, Georges
Melchi, Hans-Peter
Moran, Olivier
Application Number:
JP2003554636A
Publication Date:
May 12, 2005
Filing Date:
December 05, 2002
Export Citation:
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Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
A61K31/18; A61K31/223; A61K31/27; A61K31/325; A61K31/397; A61K31/40; A61K31/4164; A61K31/445; A61K31/4453; A61K31/505; A61K31/5375; A61P1/16; A61P3/06; A61P3/10; A61P9/00; A61P9/10; A61P31/10; A61P33/00; A61P35/00; A61P43/00; C07B61/00; C07C269/04; C07C269/06; C07C271/46; C07C271/48; C07C271/52; C07C291/04; C07C303/40; C07C311/17; C07C311/18; C07D203/12; C07D295/12; C07D205/04; C07D207/08; C07D211/46; C07D233/52; C07D233/60; C07D239/42; C07D295/084; C07D295/088; C07D295/10; C07D295/135; C07D521/00; (IPC1-7): C07C269/04; A61K31/18; A61K31/223; A61K31/27; A61K31/397; A61K31/40; A61K31/4164; A61K31/445; A61K31/4453; A61K31/505; A61K31/5375; A61P1/16; A61P3/06; A61P3/10; A61P9/00; A61P9/10; A61P31/10; A61P33/00; A61P35/00; A61P43/00; C07C269/06; C07C271/46; C07C271/52; C07C303/40; C07C311/18; C07D205/04; C07D211/46; C07D233/60; C07D239/42; C07D295/12
Attorney, Agent or Firm:
Hajime Tsukuni
Fumio Shinoda