Substitution pyrrolidine 2- Carboxamide - Ef Hoffman-La Roche Akchengezel Shaft

Title:

Substitution pyrrolidine 2- Carboxamide

Document Type and Number:

Japanese Patent JP6067108

Kind Code:

B2

Abstract:

There are provided compounds of the formula wherein X, Y, Z, R1, R2 and R3 are as described herein and enantiomers and pharmaceutically acceptable salts and esters thereof. The compounds are useful as anticancer agents.

Inventors:

David Kobitz, David Joseph
Chu, Shin-Chi
Ehrlich, George
Liu, Chin-Jun
Michelle, Hanspeter
Vu, Bin Tan
Ciao, Chun Lin

Application Number:

JP2015514443A

Publication Date:

January 25, 2017

Filing Date:

May 27, 2013

Export Citation:

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Assignee:

Ef Hoffman-La Roche Akchengezel Shaft

International Classes:

C07D207/16; A61K31/401; A61K31/4025; A61K31/437; A61K31/454; A61K31/496; A61K31/5377; A61K31/675; A61K31/7056; A61K31/77; A61P1/00; A61P11/00; A61P13/08; A61P15/00; A61P35/00; C07D401/12; C07D405/12; C07D471/04; C07F9/572; C07H5/06; C07H13/08

Domestic Patent References:

JP2012502940A

Foreign References:

US20120010235
WO2011098398A1

Attorney, Agent or Firm:

Sonoda/Kobayashi Patent Business Corporation

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