Substitution sulfonamide compound

Japanese Patent JP6262743

B2

The invention is concerned with the compounds of formula (I): and salts thereof, wherein X, Y, Z, R1, R2, R3, R3′, R4, R5 and R6 are defined in the detailed description and claims. In addition, the present invention relates to methods of manufacturing and using the compounds of Formula (I) as well as pharmaceutical compositions containing such compounds. The compounds may be useful in treating diseases and conditions mediated by TRPA1, such as pain.

Brotherton-Place, Christine Yee
Chen, Huifen
Chang, Shaochin
Chen, Gee
Ericson, Sean David
Estrada, Anthony
Kim, Kyung Jin
Ri, honju
Ravi, Allen John
Lysikatos, Joseph Pee
Chang, Imin
Seo, Sung-Saw
Wofclitch, Peter Michael
Lee Lin

JP2015533579A

January 17, 2018

September 26, 2013

Click for automatic bibliography generation  

F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT

C07C311/18; A61K31/18; A61K31/337; A61K31/402; A61K31/415; A61K31/4418; A61K31/444; A61K31/4965; A61K31/50; A61K31/501; A61K31/505; A61K31/506; A61P1/00; A61P11/00; A61P11/06; A61P11/14; A61P13/02; A61P17/04; A61P19/02; A61P27/16; A61P29/00; A61P43/00; C07C311/20; C07D213/40; C07D231/18; C07D237/08; C07D239/26; C07D241/12; C07D295/135; C07D305/06; C07D305/08; C07D401/04; C07D401/12; C07D403/04; C07D403/12; C07D409/12; C07D409/14

WO2014135617A1

PubChem [online],2009年 5月29日,CID 38528677
PubChem [online],2009年 5月29日,CID 35394890
PubChem [online],2011年 5月20日,CID 52839500
PubChem [online],2011年 5月20日,CID 52839502
PubChem [online],2010年 7月23日,CID 46487071
PubChem [online],2010年 7月23日,CID 46466818
REGISTRY(STN)[online],2017年 6月15日,CAS 登録番号:1371970-28-3等

Patent business corporation Tsukuni

Previous Patent: Progressive image processing using data URI reinforcement

Next Patent: JPS6262744