Title:
SUGAR DERIVATIVE OF PROTOCATECHUIC ALDEHYDES
Document Type and Number:
Japanese Patent JPH0363224
Kind Code:
A
Abstract:
NEW MATERIAL:A compound expressed by formula I (R1 is H or benzoyl; R2 is alkyl).
EXAMPLE: Methyl-4,6-O-(3',4'-dibenzoyloxybenzylidene)-α-D-glucopyranoside.
USE: Antiphlogistics for treating chronic rheumatism. The compound expressed by formula I has toxicity lower than that of protocatechuic aldehyde and is more effective in reduced dose.
PREPARATION: Dibenzoyloxybenzaldehyde expressed by formula II is converted to acetal compound thereof by lower alcohol and the resultant acetal compound is reacted with saccharide derivative expressed by formula III and, as necessary, the reaction product is further subjected to ammonolysis to provide the compound expressed by formula I.
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Inventors:
INADA KAZUYOSHI
NODA MIKUO
KIMURA FUMIHIKO
NODA MIKUO
KIMURA FUMIHIKO
Application Number:
JP20090389A
Publication Date:
March 19, 1991
Filing Date:
August 02, 1989
Export Citation:
Assignee:
KUREHA CHEMICAL IND CO LTD
International Classes:
C07H9/04; A61K31/70; A61P29/00; C07H15/04; (IPC1-7): A61K31/70; C07H9/04
Attorney, Agent or Firm:
Hirotoyo Miyata (1 person outside)