Title:
E-およびP-セレクチンの両方のための糖模倣物アンタゴニスト
Document Type and Number:
Japanese Patent JP2007524658
Kind Code:
A
Abstract:
Compounds and methods are provided for modulating in vitro and in vivo processes mediated by selectin binding. More specifically, selectin modulators and their use are described, wherein the selectin modulators that modulate (e.g., inhibit or enhance) a selectin-mediated function comprise particular glycomimetics linked to a member of a class of compounds termed BASAs (Benzyl Amino Sulfonic Acids).
Inventors:
Magnani, John El.
Patton, John Tea. Junior
Sarkar, Arun Khe.
Patton, John Tea. Junior
Sarkar, Arun Khe.
Application Number:
JP2006541392A
Publication Date:
August 30, 2007
Filing Date:
November 18, 2004
Export Citation:
Assignee:
Glycomimetics, Incorporated
International Classes:
C07H17/04; A61K31/7048; A61K31/7056; A61K31/706; A61K31/726; A61P1/04; A61P7/00; A61P7/02; A61P9/10; A61P11/00; A61P11/06; A61P17/02; A61P19/02; A61P19/10; A61P25/00; A61P29/00; A61P31/04; A61P35/00; A61P37/06; A61P37/08; A61P43/00; C07H3/06; C07H13/08; C07H13/10; C07H15/18; C07H15/26
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita