Title:
糖標的化治療剤
Document Type and Number:
Japanese Patent JP7434248
Kind Code:
B2
Abstract:
Several embodiments of the present disclosure relate to therapeutic compositions configured to target the liver of a subject and that are useful in the treatment or prevention of one or more of transplant rejection, autoimmune disease, food allergy, and immune response against a therapeutic agent. In several embodiments, the compositions are configured to target the liver and deliver antigens to which tolerance is desired. In several embodiments, the compositions are configured for clearance of a circulating protein or peptide or antibody associated with one or more of the above-mentioned maladies. Methods and uses of the compositions for induction of immune tolerance are also disclosed herein.
Inventors:
Jeffrey A. Hubbell
David Scott Wilson
David Scott Wilson
Application Number:
JP2021173077A
Publication Date:
February 20, 2024
Filing Date:
October 22, 2021
Export Citation:
Assignee:
Ecole Polytechnique Federale de Lausanne (EPFL)
International Classes:
C07K14/435; A61K38/02; A61P37/06; C07K14/62; C07K17/10
Domestic Patent References:
| JP2013516967A | ||||
| JP2007312776A | ||||
| JP7082045B2 |
Foreign References:
| WO2013121296A1 | ||||
| WO2012167088A1 |
Other References:
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY,2012年,Vol.134,pp.1978-1981
Attorney, Agent or Firm:
Michiko Matsutani
Norifumi Tomita
Fumio Inai
Manami Sasakura
Yusuke Shirae
Norifumi Tomita
Fumio Inai
Manami Sasakura
Yusuke Shirae
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