Title:
スルホンアミド誘導体
Document Type and Number:
Japanese Patent JP4517047
Kind Code:
B2
Abstract:
The present invention relates to a sulfonamide derivative which is useful as an active ingredient of pharmaceutical preparations. The sulfonamide derivatives of the present invention have CCR3 (CC type chemokine receptor) antagonistic activity, and can be used for the prophylaxis and treatment of diseases associated with CCR3 activity, in particular for the treatment of asthma, atopic dermatitis, allergic rhinitis and other inflammatory/immunological disorders.
Inventors:
Re Inf
Akihiko Watanabe
Timothy B. Lowwinger
Kevin bacon
Norihiro Kawamura
Takuya Shintani
Tetsuo Kikuchi
Toshiya Moriwaki
Klaus Urbans
Keiko Fukushima
Numanami Rinko
Takashi Yoshino
Toshiki Murata
Megumi Yamauchi
Hiroko Yoshino
Akihiko Watanabe
Timothy B. Lowwinger
Kevin bacon
Norihiro Kawamura
Takuya Shintani
Tetsuo Kikuchi
Toshiya Moriwaki
Klaus Urbans
Keiko Fukushima
Numanami Rinko
Takashi Yoshino
Toshiki Murata
Megumi Yamauchi
Hiroko Yoshino
Application Number:
JP2003526406A
Publication Date:
August 04, 2010
Filing Date:
September 04, 2002
Export Citation:
Assignee:
Axikin Pharmaceuticals, Inc.
International Classes:
C07C311/18; A61K31/18; A61K31/40; A61K31/4025; A61K31/4035; A61K31/437; A61K31/4375; A61K31/4406; A61K31/445; A61K31/4453; A61K31/4465; A61K31/4468; A61K31/4523; A61K31/454; A61K31/495; A61K31/496; A61K31/4985; A61K31/5375; A61K31/551; A61P5/16; A61P9/10; A61P11/02; A61P11/06; A61P25/28; A61P27/16; A61P29/00; A61P31/18; A61P35/00; A61P37/00; A61P37/02; A61P37/08; A61P43/00; C07C311/29; C07C323/67; C07D207/14; C07D207/48; C07D209/08; C07D209/44; C07D211/14; C07D211/26; C07D211/28; C07D211/58; C07D211/96; C07D213/65; C07D213/70; C07D213/71; C07D213/75; C07D213/76; C07D213/80; C07D241/04; C07D241/06; C07D243/08; C07D257/04; C07D295/088; C07D295/12; C07D295/13; C07D295/194; C07D295/22; C07D295/26; C07D307/14; C07D333/38; C07D333/40; C07D471/04; C07D487/04; C07D487/08
Domestic Patent References:
| JP11147872A |
Foreign References:
| US3819639 | ||||
| WO2001032604A1 | ||||
| US2275354 | ||||
| WO1999004794A1 |
Other References:
DELARGE,J.,New antiinflammatory derivatives of pyridine,Annales Pharmaceutiques Francaises,1973年,Vol.31, No.6,p.467-474
SAARI,W.S. et al,Synthesis and evaluation of some nitrobenzenesulfonamides containing nitroisopropyl and (ureidooxy)methyl groups as novel hypoxic cell selective cytotoxic agents,Journal of medicinal chemistry,1991年,Vol.34, No.10,p.3132-3138
MASTRUKOVA T.A. et al.,The application of the Hammett equation to the theory of tautomeric equilibrium-II : Tautomerism of α-arylsulphaminopyridines,Tetrahedron,1963年,Vol.19, No.2,p.357-372
SAARI,W.S. et al,Synthesis and evaluation of some nitrobenzenesulfonamides containing nitroisopropyl and (ureidooxy)methyl groups as novel hypoxic cell selective cytotoxic agents,Journal of medicinal chemistry,1991年,Vol.34, No.10,p.3132-3138
MASTRUKOVA T.A. et al.,The application of the Hammett equation to the theory of tautomeric equilibrium-II : Tautomerism of α-arylsulphaminopyridines,Tetrahedron,1963年,Vol.19, No.2,p.357-372
Attorney, Agent or Firm:
Aoyama Aoi
Mitsutaka Iwasaki
Yasuo Shibata
Mitsutaka Iwasaki
Yasuo Shibata