Title:
フッ化硫黄（ＶＩ）化合物およびそれの製造方法
Document Type and Number:
Japanese Patent JP7227946
Kind Code:
B2
Abstract:
This application describes a compound represented by Formula (I): (I) wherein: Y is a biologically active organic core group comprising one or more of an aryl group, a heteroaryl aryl group, a nonaromatic hydrocarbyl group, and a nonaromatic heterocyclic group, to which Z is covalently bonded; n is 1, 2, 3, 4 or 5; m is 1 or 2; Z is O, NR, or N; X1 is a covalent bond or -CH2CH2-, X2 is O or NR; and R comprises H or a substituted or unsubstituted group selected from an aryl group, a heteroaryl aryl group, a nonaromatic hydrocarbyl group, and a nonaromatic heterocyclic group. Methods of preparing the compounds, methods of using the compounds, and pharmaceutical compositions comprising the compounds are described as well.
Inventors:
Jajar Don
Kay Barry Sharpless
Jeffrey W. Kelly
Alexandra Balanchuck
Wentao Chen
Kay Barry Sharpless
Jeffrey W. Kelly
Alexandra Balanchuck
Wentao Chen
Application Number:
JP2020121863A
Publication Date:
February 22, 2023
Filing Date:
July 16, 2020
Export Citation:
Assignee:
The Script Research Institute
International Classes:
C07C305/26; A61K31/185; A61K31/351; A61K31/4245; A61K31/428; A61K38/08; A61K38/095; A61K38/10; A61K38/12; A61K38/17; A61P3/10; A61P5/10; A61P21/00; A61P25/28; C07B59/00; C07C309/78; C07C313/06; C07D271/06; C07D277/82; C07D309/10; C07K14/575
Domestic Patent References:
| JP3220195A | ||||
| JP51125225A | ||||
| JP2223570A |
Foreign References:
| WO2010113151A1 | ||||
| WO2006060654A2 |
Other References:
Kreimeyer, Annett; Laube, Bodo; Sturgess, Mike; Goeldner, Maurice; Foucaud, Bernard,Evaluation and Biological Properties of Reactive Ligands for the Mapping of the Glycine Site on the N-Methyl-D-aspartate (NMDA) Receptor,Journal of Medicinal Chemistry,1999年,42(21),,4394-4404
Attorney, Agent or Firm:
Kawaguchi International Patent Office