SURVIVIN TARGET PEPTIDE

Japanese Patent JP2018080159

A

PROBLEM TO BE SOLVED: To provide a peptide that can bind to a region which contributes to the formation of a chromosome passenger complex (CPC) in Survivin protein being a protein most specific to cancer at high affinity, and an application of the peptide in treating or diagnosing cancer.SOLUTION: There are provided a peptide derived from INCENP or Borealin which can bind to Survivin having a specific amino acid sequence or its variant sequence, a conjugate in which one or more components bind to the peptide, and a composition which contains the peptide or the conjugate and is used in treating or diagnosing cancer.SELECTED DRAWING: None

WO/1996/025432	HUMAN G-PROTEIN COUPLED RECEPTOR
WO/1999/032516	PHARMACEUTICAL COMPOSITIONS CONTAINING THE LONG PENTRAXIN PTX3
JP2003530841	Description: Therapeutic compounds and methods

FUCHIGAMI TAKESHI
NAKAYAMA MORIO
YOSHIDA SAKURA
ISHIKAWA NATSUMI

JP2017205389A

May 24, 2018

October 24, 2017

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UNIV NAGASAKI

C07K14/47; A61B5/055; A61B6/03; A61K38/04; A61K45/00; A61K45/08; A61K47/42; A61K47/64; A61K49/04; A61K49/14; A61K49/22; A61K51/08; A61P35/00; A61P35/02; C07K7/00

ANALYTICAL CHEMISTRY, vol. 85, JPN6021024743, 2013, pages 11185 - 11188, ISSN: 0004538290
THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 282, no. 48, JPN6021024741, 30 November 2007 (2007-11-30), pages 35018 - 35023, ISSN: 0004538291

Takashima Ichi
Kyoko Doi
Mitsunori Kamata
Yaeko Tamura
Junzo Koike
Hirofumi Toma
Atsuko Akai
Tomiya Tozaki

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