Title:
コルヒチンの徐放性製剤およびその使用方法
Document Type and Number:
Japanese Patent JP6887043
Kind Code:
B2
Abstract:
Pharmaceutical compositions of colchicine for once-a-day oral administration are provided. The formulations comprise a sustained-release component and an optional immediate-release component, the compositions of which can be selectively adjusted, respectively, to release the active ingredient along a pre-determined or desired release profile. The formulation comprises a release-retarding agent comprising HMPC and lactose monohydrate. Methods of treating or preventing cardiovascular disease and/or inflammatory disease in mammalian subjects comprising the administration of the novel formulations disclosed herein is also provided.
Inventors:
Riel, Suzanne
Application Number:
JP2020077153A
Publication Date:
June 16, 2021
Filing Date:
April 24, 2020
Export Citation:
Assignee:
Murray and Pool Enterprises Limited
International Classes:
A61K31/165; A61K9/06; A61K9/08; A61K9/14; A61K9/16; A61K9/22; A61K9/52; A61K9/70; A61K31/22; A61K31/366; A61K31/40; A61K31/505; A61K45/00; A61K47/02; A61K47/04; A61K47/12; A61K47/14; A61K47/18; A61K47/20; A61K47/26; A61K47/32; A61K47/34; A61K47/36; A61K47/38; A61K47/42; A61P7/02; A61P9/00; A61P11/00; A61P19/06; A61P25/28; A61P27/02
Domestic Patent References:
| JP2011140498A | ||||
| JP2012236846A | ||||
| JP2013510873A | ||||
| JP2000034224A | ||||
| JP2012519725A | ||||
| JP6480420B1 |
Foreign References:
| CN101732274A |
Other References:
医薬品添加物事典2007,薬事日報社,2007年 7月25日,第1刷,pp.150-151
Attorney, Agent or Firm:
Shoichi Okuyama
Arihara Koichi
Matsushima Tetsuo
Ayako Nakamura
Satoshi Morimoto
Yu Tanaka
Tokumoto Koichi
Akiko Mizushima
Arihara Koichi
Matsushima Tetsuo
Ayako Nakamura
Satoshi Morimoto
Yu Tanaka
Tokumoto Koichi
Akiko Mizushima