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Title:
Syk inhibitor
Document Type and Number:
Japanese Patent JP6159028
Kind Code:
B2
Abstract:
wherein X1, X2, X3, R2, R3, R4, R5, and Y are as described herein. The present disclosure further provides pharmaceutical compositions that include a compound of Formula I, or pharmaceutically acceptable salts thereof, and methods of using these compounds and compositions to treat conditions mediated by Syk.

Inventors:
Curry, Kevin S.
Do, Jimin
Farandy, Julie
Guerrero, Juan A.
Katana, Ashley A.
Kato, Daryl
Razor With, Scott E.
Li, Jayao
Link, John Oh.
My, nicholas
Notte, Gregory
Pyun, Hyun-Jun
Sangi, michael
Schmidt, Aaron See.
Schlier, Adam Jay.
Stevens, Kirk El.
Ben Katara Mani, Chandrasekhar
Watkins, William Jay.
Yang, Zen-You
Jeff Zabrocchi
Zipfer, Sheila
Roh, Jennifer
Lee, Sun H.
Zao, Zhong Dong
Croff, Jeffrey
Sue, Junjung
Peter Bromgren
Mitchell, Scott A.
Sion, jin min
Chandrasekhar, Jayala Man
Application Number:
JP2016531884A
Publication Date:
July 05, 2017
Filing Date:
July 31, 2014
Export Citation:
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Assignee:
Gilead Sciences, Inc.
International Classes:
C07D403/12; A61K31/428; A61K31/437; A61K31/496; A61K31/497; A61K31/4985; A61K31/5377; A61K31/5383; A61K31/553; A61P1/04; A61P7/04; A61P7/06; A61P11/06; A61P17/00; A61P17/06; A61P19/02; A61P21/00; A61P21/04; A61P25/00; A61P29/00; A61P35/00; A61P35/02; A61P37/02; A61P37/08; A61P43/00; C07D401/14; C07D403/14; C07D405/14; C07D417/12; C07D417/14; C07D471/04; C07D487/04; C07D495/04; C07D498/04; C07D519/00
Domestic Patent References:
JP2012502029A
JP2011511835A
JP2011529932A
Foreign References:
WO2012057262A1
WO2013014060A1
WO2012080236A1
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita