Title:
水疱性口内炎ウイルスの相乗的弱毒化、そのベクター及びその免疫原性組成物
Document Type and Number:
Japanese Patent JP5779226
Kind Code:
B2
Abstract:
The present invention broadly relates to the synergistic attenuation of vesicular stomatitis virus (VSV), More particularly, the invention relates to the identification of combined mutation classes which synergistically attenuate the pathogenicity of VSV vectors in mammals and immunogenic compositions thereof.
Inventors:
Clarke, david, kirkwood
Hendry, Roger, Michelle
Udem, Stefan, A.
Perks, christopher, lee
Hendry, Roger, Michelle
Udem, Stefan, A.
Perks, christopher, lee
Application Number:
JP2013253335A
Publication Date:
September 16, 2015
Filing Date:
December 06, 2013
Export Citation:
Assignee:
Weiss LRC
International Classes:
C12N15/09; A61K35/766; A61K48/00; A61P31/00; A61P31/04; A61P31/14; A61P31/16; A61P31/18; A61P31/20; A61P31/22; A61P35/00; C07K14/145; C12N7/04; C12N15/86; A61K39/00
Domestic Patent References:
| JP2004501639A |
Foreign References:
| WO2004113517A1 | ||||
| WO2003046506A1 | ||||
| WO2004022716A1 |
Other References:
J. Virol., 1999, Vol.73, p.3723-3732
Proc. Natl. Acad. Sci. U.S.A., 1998, Vol.95, p.3501-3506
Virology, 2000, Vol.268, p.112-121
Proc. Natl. Acad. Sci. U.S.A., 1998, Vol.95, p.3501-3506
Virology, 2000, Vol.268, p.112-121
Attorney, Agent or Firm:
Hiroshi Kobayashi
Norio Omori
Yasuhito Suzuki
Norio Omori
Yasuhito Suzuki