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Title:
オートファジーの促進剤としての相乗作用組成物
Document Type and Number:
Japanese Patent JP7307715
Kind Code:
B2
Abstract:
The invention relates to a synergistic composition comprising a dry extract of plant of genus Galeopsis and a compound promoting autophagy selected from biotin and R-N1-spermidine or a salt thereof, wherein R is hydrogen or methyl and mixtures thereof. The synergistic compositions according to the invention may be in the form of a topical formulation or oral formulation and is useful as a promoter of autophagy especially in cells of human scalp hair follicles and in promoting hair growth and/or in the treatment of hair thinning or hair loss.

Inventors:
Giuliani Gianmaria
Paus Ralph
Grimaldi Benedetto
Marzani Barbara
Baroni Sergio
Application Number:
JP2020504725A
Publication Date:
July 12, 2023
Filing Date:
August 02, 2018
Export Citation:
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Assignee:
Giuriani Societa Per Athioni
International Classes:
A61K36/53; A61K8/41; A61K8/49; A61K8/9789; A61K9/10; A61K9/14; A61K9/16; A61K9/20; A61K9/48; A61K31/132; A61K31/4188; A61P17/14; A61P43/00; A61Q1/00; A61Q5/00; A61Q7/00
Domestic Patent References:
JP2010529960A
JP2003002839A
JP2004506656A
JP2005519069A
JP2008534464A
JP2014510783A
JP2015522647A
Foreign References:
WO2015063678A1
Other References:
Journal of Investigative Dermatology,2016年,Vol. 136, No. 9, Supp. 2,p. S196, article number 209
PLoS ONE,2011年,Vol. 6, No. 7, e22564,pp.1-12
nature cell biology,2009年,Vol. 11, No. 11,pp. 1305-1314
Skin Appendage Disorders,2017年04月,Vol. 3,pp. 166-169
Attorney, Agent or Firm:
Masao Sekiguchi