Title:
SYNTHESIS OF ENANTIOMERIC 3-(SUBSTITUTED PHENYL)-4- (3-HYDROXYPROPYL)CYCLOHEXANONOL
Document Type and Number:
Japanese Patent JPS59157042
Kind Code:
A
Abstract:
Racemic endo- and exo-1-methoxybicyclo[2.2.2]oct-5- ene-2-carboxylic acids are starting materials for a novel and efficient synthesis of chiral 3R-[2-hydroxy-4-(1,1-dimethylheptyl)phenyl]-4R-(3-hydroxypropyl)-1R-cyclohexanol, a compound having valuable central nervous system (CNS) activity, particularly as an analgesic and as an antiemetic.
Inventors:
FURANKU JIYON AABAN
Application Number:
JP1982184A
Publication Date:
September 06, 1984
Filing Date:
February 06, 1984
Export Citation:
Assignee:
PFIZER
International Classes:
C07C41/00; C07C41/26; C07C43/23; C07C51/487; C07C62/34; C07C67/00; C07C69/738; C07C67/303; C07C67/31; C07C69/734; (IPC1-7): C07C41/26; C07C43/23; C07C67/303; C07C67/31; C07C69/734; C07C69/738
Attorney, Agent or Firm:
Kyozo Yuasa