Title:
SYNTHESIS OF OPTICALLY ACTIVE PHENYLALANINE ANALOGUE VIA MICROBIAL TRANSFORMATION
Document Type and Number:
Japanese Patent JP2001112495
Kind Code:
A
Abstract:
To provide a biocatalytic process for producing an optically active phenylalanine analogues from an arylacrylic acid.
A yeast fungus, Rhodotorula graminis, including phenylalanine ammonialyase introduces an ammonia molecule into the double bond of a stereospecifically 3-position substituted acrylic acid. As a substituent in the 3-position of acrylic acid, are cited an aromatic ring, for example, a substituted phenyl group, a five-membered aromatic heterocyclic ring, a 6-membered heterocyclic ring and the like.
Inventors:
WEIGUO RIU
Application Number:
JP29403099A
Publication Date:
April 24, 2001
Filing Date:
October 15, 1999
Export Citation:
Assignee:
GREAT LAKES CHEMICAL CORP
International Classes:
C12N1/14; C12P13/04; C12P13/22; C12R1/645; (IPC1-7): C12P13/22
Attorney, Agent or Firm:
Yoshihiro Tsunoda (4 outside)
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