Title:
ビシナルジフルオロ芳香族化合物及びその中間体の合成
Document Type and Number:
Japanese Patent JP4313217
Kind Code:
B2
Abstract:
A method of preparing vicinal difluoro aromatic compounds in high yield from hydroxy aromatic compounds using various bases and a method of preparing intermediates thereof. A method for making a vicinal difluoro halogenated aromatic compound including providing a tetrafluoro derivative of a halogen substituted aromatic compound, wherein the tetrafluoro derivative has two fluorine atoms on each of two adjacent carbons and at least one additional halogen substituent; reacting the tetrafluoro derivative with a reducing agent in presence of a base for a reaction time sufficient to form the vicinal difluoro halogenated aromatic compound containing two vicinal fluorine substituents and the at least one additional halogen substituent, wherein the reducing agent is used in a reducing agent effective amount sufficient to retain the at least one additional halogen substituent.
Inventors:
Axel Clauk-Jakobs
Kathryn Sue Hayes
Reiner Reinhard Wilhelm Tege
William Jack Castile, Jr.
Gori Sankar Ral
Kathryn Sue Hayes
Reiner Reinhard Wilhelm Tege
William Jack Castile, Jr.
Gori Sankar Ral
Application Number:
JP2004025829A
Publication Date:
August 12, 2009
Filing Date:
February 02, 2004
Export Citation:
Assignee:
AIR PRODUCTS AND CHEMICALS INCORPORATED
International Classes:
C07C17/23; C07B39/00; C07C17/18; C07C25/22; C07C45/29; C07C45/51; C07C49/697
Domestic Patent References:
| JP2002255870A | ||||
| JP2001354600A |
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Tetsuji Koga
Nagasaka Tomoyasu
Yoshihiro Kobayashi
Satoshi Deno
Takashi Ishida
Tetsuji Koga
Nagasaka Tomoyasu
Yoshihiro Kobayashi
Satoshi Deno