PURPOSE: To obtain a preparation capable of orally administering a peptide having promoting action on learned behavior or bettering action on learning disturbance.

CONSTITUTION: A composition as a nucleus contains a peptide such as pGlu-Asn- Ser-Pro-Arg-Gly-NH2 having promoting action on learned behavior or bettering action on learning disturbance and its pharmacological effect drawing a bell- shaped curve and a proteinase inhibitor and the nucleus is coated with an enteric coating to give the objective preparation for oral administration.