To obtain the subject synthetic suppressant capable of suppressing the synthesis of heat shock protein in cells and curing diseases such as cancer and multiple sclerosis by containing a specific aloin derivative as an active ingredient.
This synthetic suppressant contains an aloin derivative of formula I (R1 is a hexose residue excluding a hydroxy group at the 1-position of hexose; R2 is a 1-3 C hydroxyalkyl). As this aloin derivative, aloin of formula II is preferable. Aloin is contained in a crude drug such as aloe and the like and obtained by extracting e.g. aloe with water (e.g. cold water, warm water or boiling water) or an organic solvent. By this suppressant, cancers relating to the change of normal cells to malignant tumors and the reduce of effect in the thermotherapy and autoimmune diseases such as multiple sclerosis and the like relating to the occurrence caused by heat shock protein from 16kDa to 40kDa in molecular weight can be effectively cured.
TSUZUKI TOMOKO
SHIRAGAMI TOSHIMI
MORINO MASAYOSHI
YOSHIKUMI CHIKAO
