SYSTEM FOR TREATING PULMONARY INFECTION

Title:

SYSTEM FOR TREATING PULMONARY INFECTION

Document Type and Number:

Japanese Patent JP2017193589

Kind Code:

A

Abstract:

PROBLEM TO BE SOLVED: To provide a system for treating pulmonary infection.SOLUTION: According to the present invention, there is provided a method for treating various pulmonary infections including mycobacterial infections by providing a system for delivery of an aerosolized liposomal formulation via inhalation. In one aspect, the present invention provides a system for treating or providing prophylaxis against a pulmonary infection. In one embodiment, the system comprises a pharmaceutical formulation comprising: a liposomal complexed aminoglycoside (here, the formulation is a dispersion (e.g., a liposomal solution or suspension), the lipid component of the liposome consists of electrically neutral lipids); and a nebulizer which generates an aerosol of the pharmaceutical formulation at a rate greater than about 0.53 g per minute.SELECTED DRAWING: None

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Inventors:

WALTER PERKINS
VLADIMIR MALININ
LI XINGONG
BRIAN MILLER
DOMINIQUE SEIDEL
PHILIPP HOLZMANN
HARALD SCHULZ
HAHN MICHAEL

Application Number:

JP2017151435A

Publication Date:

October 26, 2017

Filing Date:

August 04, 2017

Export Citation:

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Assignee:

INSMED INC

International Classes:

A61K31/7036; A61K9/12; A61K9/127; A61K47/24; A61K47/28; A61P31/06

Domestic Patent References:

JP2002318193A	2002-10-31
JP2008531197A	2008-08-14
JP2012505265A	2012-03-01

Other References:

PEDIATRIC PULMONOLOGY, vol. Vol. 42, Suppl. 30, JPN7017001216, October 2007 (2007-10-01), pages 356 - 357, ISSN: 0004096700
THORAX, vol. Vol. 52(Suppl 2), JPN6017012223, 1997, pages 1 - 24, ISSN: 0003788821

Attorney, Agent or Firm:

Hidesaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto

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