Title:
増殖抑制性脂質由来生物活性化合物の全身送達方法およびシステム
Document Type and Number:
Japanese Patent JP5888849
Kind Code:
B2
Abstract:
A system and method for optimizing the systemic delivery of growth-arresting lipid-derived bioactive drugs or gene therapy agents to an animal or human in need of such agents utilizing nanoscale assembly systems, such as liposomes, resorbable and non-aggregating nanoparticle dispersions, metal or semiconductor nanoparticles, or polymeric materials such as dendrimers or hydrogels, each of which exhibit improved lipid solubility, cell permeability, an increased circulation half life and pharmacokinetic profile with improved tumor or vascular targeting.
More Like This:
| JPS5989633 | MANUFACTURE OF LIPOSOME IN AQUEOUS PHASE |
| JP2020503280 | Hydroxybenzoic acid derivatives, methods and uses thereof |
| JP2024512088 | fibril peptide |
Inventors:
Kester mark
Stalker, thomas
Lowe, Tao
James Adair
Kim, Youn, Shin
Stalker, thomas
Lowe, Tao
James Adair
Kim, Youn, Shin
Application Number:
JP2010262287A
Publication Date:
March 22, 2016
Filing Date:
November 25, 2010
Export Citation:
Assignee:
THE PENN STATE RESEARCH FOUNDATION
International Classes:
A61K9/127; A61K9/16; A61K9/51; A61K31/164; A61K47/18; A61K47/28; A61K47/34; A61K48/00; A61P3/10; A61P9/00; A61P9/10; A61P35/00; A61P43/00; C12N15/88; A61K
Domestic Patent References:
| JP2006524707A | ||||
| JP9508900A | ||||
| JP10510805A | ||||
| JP2002533394A | ||||
| JP9110722A | ||||
| JP10506395A | ||||
| JP10506622A | ||||
| JP2001510808A | ||||
| JP2002536316A |
Foreign References:
| US6395713 |
Attorney, Agent or Firm:
Yusuke Hiraki
Satoshi Fujita
Eiichi Arai
Natsuo Tanaka
Naoko Kikuta
Ai Fujii
Iwasaki Masaji
Satoshi Fujita
Eiichi Arai
Natsuo Tanaka
Naoko Kikuta
Ai Fujii
Iwasaki Masaji