Title:
全ゲノム配列データのデノボアセンブリのためのシステム、方法及び媒体
Document Type and Number:
Japanese Patent JP6735348
Kind Code:
B2
Abstract:
Described are computer-implemented methods, systems, and media for de novo phased diploid assembly of nucleic acid sequence data generated from a nucleic acid sample of an individual utilizing nucleic acid tags to preserve long-range sequence context for the individual such that a subset of short-read sequence data derived from a common starting sequence shares a common tag. The phased diploid assembly is achieved without alignment to a reference sequence derived from organisms other than the individual. The methods, systems, and media described are computer-resource efficient, allowing scale-up.
Inventors:
David, David
Marks, Patrick
Schnar-Levin, Michael
Weissenfeld, Neil
Marks, Patrick
Schnar-Levin, Michael
Weissenfeld, Neil
Application Number:
JP2018542282A
Publication Date:
August 05, 2020
Filing Date:
August 19, 2016
Export Citation:
Assignee:
10x Genomics, Inc.
International Classes:
C12Q1/6869; G16B30/20; C12M1/00; C12N15/09; G16B25/00; G16B30/10
Foreign References:
| US20150379196 | ||||
| US20150133344 | ||||
| US20140323316 | ||||
| US20120041727 | ||||
| US20110257889 |
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto