Title:
TMPRSS6 IRNA COMPOSITIONS AND METHODS FOR USE THEREOF
Document Type and Number:
Japanese Patent JP2023061967
Kind Code:
A
Abstract:
To provide methods of treating subjects having a TMPRSS6 associated disorder, e.g., an iron overload associated disorder, such as β-thalassemia or hemochromatosis.SOLUTION: The invention relates to RNAi agents, e.g., double- stranded RNAi agents, targeting the TMPRSS6 gene, and methods of using such RNAi agents to inhibit expression of TMPRSS6.SELECTED DRAWING: None
Inventors:
James Butler
Brian bettencourt
Callantottil Gee Rajib
Martin Meier
Klaus Karise
Brian bettencourt
Callantottil Gee Rajib
Martin Meier
Klaus Karise
Application Number:
JP2023010415A
Publication Date:
May 02, 2023
Filing Date:
January 26, 2023
Export Citation:
Assignee:
ALNYLAM PHARMACEUTICALS, INC.
International Classes:
A61K31/713; A61K35/76; A61K47/54; A61K48/00; A61P3/00; A61P7/00; A61P7/06; A61P25/00; A61P25/16; A61P25/28; A61P39/02; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/113; C12N15/63
Attorney, Agent or Firm:
Yamato Kento
Norifumi Tomita
Fumio Inai
Manami Sasakura
Norifumi Tomita
Fumio Inai
Manami Sasakura
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