Title:
TNF super family collectin fused protein
Document Type and Number:
Japanese Patent JP6002903
Kind Code:
B2
Abstract:
The present invention refers to a fusion protein comprising a TNF-superfamily (TNFSF) cytokine or a receptor binding domain thereof fused to a collectin trimerization domain, to a nucleic acid molecule encoding the fusion protein, and to a cell comprising the nucleic acid molecule. The fusion protein is present as a trimeric complex or as an oligomer thereof. The fusion protein, the nucleic acid, and the cell is suitable as pharmaceutical composition or for therapeutic, diagnostic and/or research applications.
Inventors:
Oliver Hill
Christian gifers
My Norf Teaman
Marx Blanchedel
Christian gifers
My Norf Teaman
Marx Blanchedel
Application Number:
JP2010515417A
Publication Date:
October 05, 2016
Filing Date:
July 10, 2008
Export Citation:
Assignee:
Apogenics
International Classes:
C12N15/09; A01K67/027; A61K31/7088; A61K35/12; A61K38/00; A61P3/00; A61P19/02; A61P25/00; A61P29/00; A61P31/00; A61P35/00; A61P37/02; A61P37/06; A61P43/00; C07K5/083; C07K7/06; C07K7/08; C07K14/47; C07K14/525; C07K19/00; C12N1/21; C12N5/10
Domestic Patent References:
| JP2003518949A | ||||
| JP2005514061A |
Foreign References:
| US20040247563 | ||||
| WO2001042298A1 |
Other References:
J Biol Chem.(2006),Vol.281,No.26,p.18008-18014
HOLLER,N. et al.,Two adjacent trimeric Fas ligands are required for Fas signaling and formation of a death-inducing s,Mol. Cell Biol.,2003年 2月,Vol.23, No.4,pp.1428-40
SISSOEFF,L. et al.,Stable trimerization of recombinant rabies virus glycoprotein ectodomain is required for interaction,J. Gen. Virol.,2005年 9月,Vol.86, No.9,pp.2543-52
HOLLER,N. et al.,Two adjacent trimeric Fas ligands are required for Fas signaling and formation of a death-inducing s,Mol. Cell Biol.,2003年 2月,Vol.23, No.4,pp.1428-40
SISSOEFF,L. et al.,Stable trimerization of recombinant rabies virus glycoprotein ectodomain is required for interaction,J. Gen. Virol.,2005年 9月,Vol.86, No.9,pp.2543-52
Attorney, Agent or Firm:
Einzel Felix-Reinhard
Takuya Kuno
Shuichi Sumiyoshi
Takuya Kuno
Shuichi Sumiyoshi
Previous Patent: Game stand
Next Patent: A blowout tester implement and a blowout inspection device of a tire
Next Patent: A blowout tester implement and a blowout inspection device of a tire