Title:
TNFR:FC融合プロテインの安定な医薬組成物
Document Type and Number:
Japanese Patent JP6431844
Kind Code:
B2
Abstract:
The present invention relates to the stable pharmaceutical compositions comprising tumor necrosis factor receptor Fc fusion protein (TNFR:Fc). More particularly, it relates to the stable pharmaceutical compositions comprising tumor necrosis factor receptor Fc fusion protein (TNFR:Fc), phosphate-citrate buffer. It also relates to the methods of manufacturing the composition, method of administration and kits containing the same.
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Inventors:
Apte-Deshpande, Anjali, Deepak
Deokar, Bybab, Dianushwar
Modi, Rusthom, Solab
Deokar, Bybab, Dianushwar
Modi, Rusthom, Solab
Application Number:
JP2015538612A
Publication Date:
November 28, 2018
Filing Date:
October 24, 2013
Export Citation:
Assignee:
LUPIN ATLANTIS HOLDINGS SA
International Classes:
A61K38/16; A61K9/08; A61K47/02; A61K47/12; A61K47/18; A61K47/24; A61K47/26; A61P1/04; A61P17/06; A61P19/02; A61P29/00
Domestic Patent References:
| JP6199691A | ||||
| JP11500404A | ||||
| JP2005527503A | ||||
| JP2001517635A | ||||
| JP2006511457A |
Foreign References:
| WO2011141926A1 | ||||
| WO2012143418A1 |
Other References:
白木 賢太郎,タンパク質の失活や凝集を抑制する小分子添加剤,生物物理,2004年,第44巻,第2号,p.87-90
冨田 峻介,白木 賢太郎,タンパク質の劣化を抑制する溶液添加剤:非共有結合的な凝集と共有結合的な修飾,極限環境微生物学会誌(Journal of Japanese Society for Extremophiles),2010年,第9巻,第2号,p.81-89
冨田 峻介,白木 賢太郎,タンパク質の劣化を抑制する溶液添加剤:非共有結合的な凝集と共有結合的な修飾,極限環境微生物学会誌(Journal of Japanese Society for Extremophiles),2010年,第9巻,第2号,p.81-89
Attorney, Agent or Firm:
Shintaro Nogawa
Shinji Kai
Yusuke Kaneko
Kiyoshi Inamoto
Masami Tomita
Shinji Kai
Yusuke Kaneko
Kiyoshi Inamoto
Masami Tomita