Title:
金属結合モチーフを含むＩｇＧ結合ポリペプチドの標的結合ポリペプチド変異体
Document Type and Number:
Japanese Patent JP7242116
Kind Code:
B2
Abstract:
The present invention is within the field of protein engineering and purification. The invention relates to a target-binding polypeptide mutant of an IgG binding polypeptide, such as Protein A, Protein G, Protein L or Protein M, comprising a metal binding motif. More closely the invention relates to an Fc binding ligand comprising an engineered protein based on the Protein A derived Z domain, to which a calcium binding EF-loop has been introduced.
Inventors:
Hover, sofia
Kanye, Sara
Nilbe Brandt, Johan
Kanye, Sara
Nilbe Brandt, Johan
Application Number:
JP2019512905A
Publication Date:
March 20, 2023
Filing Date:
September 05, 2017
Export Citation:
Assignee:
Citiva Bioprocess R & D Activorag
International Classes:
C07K14/31; C07K1/22; C07K16/00; C07K19/00; C12N15/31; C12N15/62; C12N15/63
Domestic Patent References:
| JP7126297A | ||||
| JP2013542919A |
Other References:
ANALYTICAL CHEMISTRY,1996年11月15日,VOL:68, NR:22,PAGE(S):3939 - 3944
MOLECULAR MICROBIOLOGY,英国,1992年03月01日,VOLUME:6, ISSUE:6,PAGES:703-713
MOLECULAR MICROBIOLOGY,英国,1992年03月01日,VOLUME:6, ISSUE:6,PAGES:703-713
Attorney, Agent or Firm:
Masato Iida
Choe Yun
Kenji Tanaka
Hiroshi Ogura
Takuto Tanaka
Choe Yun
Kenji Tanaka
Hiroshi Ogura
Takuto Tanaka