Title:
ナノ粒子を用いた癌細胞の標的化
Document Type and Number:
Japanese Patent JP2010540535
Kind Code:
A
Abstract:
The present invention generally relates to polymers and macromolecules, in particular, to polymers useful in particles such as nanoparticles. One aspect of the invention is directed to a method of developing nanoparticles with desired properties. In one set of embodiments, the method includes producing libraries of nanoparticles having highly controlled properties, which can be formed by mixing together two or more macromolecules in different ratios. One or more of the macromolecules may be a polymeric conjugate of a moiety to a biocompatible polymer. In some cases, the nanoparticle may contain a drug. Other aspects of the invention are directed to methods using nanoparticle libraries.
Inventors:
Zeal Stephen Yi.
Ali Marma Column
Ali Marma Column
Application Number:
JP2010526977A
Publication Date:
December 24, 2010
Filing Date:
March 31, 2008
Export Citation:
Assignee:
BIND Biosciences, Inc.
International Classes:
A61K9/14; A61K9/08; A61K9/127; A61K9/51; A61K31/136; A61K31/337; A61K31/713; A61K47/32; A61K47/34; A61K47/48; A61K48/00; A61P1/00; A61P11/00; A61P13/08; A61P25/00; A61P35/00; C07C237/12; C07C275/16; C07C323/52; C07F9/30
Domestic Patent References:
| JP2005507857A | 2005-03-24 | |||
| JP2010509358A | 2010-03-25 |
Foreign References:
| US20050037075A1 | 2005-02-17 |
Other References:
JPN6013006760; ＣｈｅｍＭｅｄＣｈｅｍ ｖｏｌ．１, 2006, ｐ．２９９-３０２
JPN6013006762; Ｊ． Ｍｅｄ． Ｃｈｅｍ． ｖｏｌ．４６, 2003, ｐ．１９８９-１９９６
JPN6013006765; Ｂｉｏｏｒｇａｎｉｃ ａｎｄ Ｍｅｄｉｃｉｎａｌ Ｃｈｅｍｉｓｔｒｙ ｖｏｌ．１１, 2003, ｐ．４４５５-４４６１
JPN6013006762; Ｊ． Ｍｅｄ． Ｃｈｅｍ． ｖｏｌ．４６, 2003, ｐ．１９８９-１９９６
JPN6013006765; Ｂｉｏｏｒｇａｎｉｃ ａｎｄ Ｍｅｄｉｃｉｎａｌ Ｃｈｅｍｉｓｔｒｙ ｖｏｌ．１１, 2003, ｐ．４４５５-４４６１
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Masato Ozeki
Kazuya Kawamoto
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Masato Ozeki
Kazuya Kawamoto