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Title:
Targeting coagulation factors for TLT-1 on activated platelets
Document Type and Number:
Japanese Patent JP6309273
Kind Code:
B2
Abstract:
Described are procoagulant proteins which may, for example, be fusion proteins or chemical conjugates; methods of producing procoagulant proteins; polynucleotides that encode fusion proteins and cells that expresses them. Furthermore, described are procoagulant proteins for use as a medicament. Individuals that have a coagulopathy, such as haemophilia A and B with or without inhibitors, may be treated with such procoagulant proteins.

Inventors:
Eda Hilden
Bernd Peshke
Jens Breinholt
Michelle Cofors-Hansen
Application Number:
JP2013555888A
Publication Date:
April 11, 2018
Filing Date:
March 02, 2012
Export Citation:
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Assignee:
Novo Nordisk Health Care AG
International Classes:
C07K14/745; A61K38/36; A61K38/37; A61K39/395; A61P7/04; C07K1/10; C07K14/755; C07K16/28; C07K19/00; C12N15/02; C12N15/09
Domestic Patent References:
JP2013503140A
JP2007204469A
Foreign References:
WO2010115866A1
WO2009140598A1
US20080131423
WO2006096828A2
Other References:
GIOMARELLI BARBARA,THROMBOSIS AND HAEMOSTASIS,米国,SCHATTAUER GMBH,2007年 6月 1日,V97 N6,P955-964
Attorney, Agent or Firm:
Yasuhiko Murayama
Shinya Mitsuhiro
Tatsuhiko Abe