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Title:
TASTE-MASKED MICROCAPSULE COMPOSITION AND METHOD OF MANUFACTURE
Document Type and Number:
Japanese Patent JP2006225397
Kind Code:
A
Abstract:

To provide a taste-masked microcapsule composition of a water-soluble drug, which can effectively mask the taste and immediately releases the drug, when passing through the mouth of a patient.

This taste-masked microcapsule composition of a water-soluble drug, the composition comprising microcapsules of the water-soluble drug (ranitidine such as H2 antagonist) in a polymeric material consisting essentially of one or more polymers selected from the group consisting of ethyl cellulose, cellulose acetate phthalate, cellulose acetate butyrate, polymethacrylates, hydroxypropyl methyl cellulose phthalate; carboxymethyl ethylcellulose; polylactic acid and combinations thereof, said polymeric material constituting approximately 30 wt.% to 65 wt.% of the composition.


Inventors:
FRIEND DAVID R
NG STEVEN
SARABIA RAFAEL E
WEBER THOMAS P
GEOFFROY JEAN-MARIE
Application Number:
JP2006079752A
Publication Date:
August 31, 2006
Filing Date:
March 22, 2006
Export Citation:
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Assignee:
CIMA LABS INC
STANFORD RES INST INT
International Classes:
A61K9/50; A61J3/07; C07D307/52; A61K9/20; A61K9/58; A61K9/62; A61K31/341; A61K45/00; A61K47/04; A61K47/12; A61K47/32; A61K47/34; A61K47/38; A61P1/04; A61P17/04; A61P29/00; A61P37/08; B01J13/06; A61K9/00
Domestic Patent References:
JPS5030136B21975-09-29
JPS58196842A1983-11-16
JPS57197214A1982-12-03
JPS5916821A1984-01-28
JPS5665821A1981-06-03
JPS61152623A1986-07-11
JPH03118335A1991-05-20
JPH01500998A1989-04-06
JPH01502589A1989-09-07
JPH08510989A1996-11-19
JPH05500956A1993-02-25
Attorney, Agent or Firm:
Koichi Fujii
Kojiro Yoda



 
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