Title:
タキサン含有両親媒性ブロック共重合体ミセル組成物及びその製造方法
Document Type and Number:
Japanese Patent JP2011509322
Kind Code:
A
Abstract:
A taxane-containing amphiphilic block copolymer micelle composition, including taxane, an amphiphilic block copolymer containing a hydrophilic block and a hydrophobic block, and an osmolality adjusting agent, is described. Also described are a method for preparing the same composition. The composition has excellent stability so that it can prevent rapid release of a drug and can improve a desired pharmacological effect. Additionally, the method enables highly efficient preparation of the composition.
Inventors:
Lee, Suwon
Seo, Min-Hyo
Seo, Min-Hyo
Application Number:
JP2010540552A
Publication Date:
March 24, 2011
Filing Date:
October 13, 2008
Export Citation:
Assignee:
SAMYANG CORPORATION
International Classes:
C08L67/00; A61K9/10; A61K31/337; A61K47/34; A61P35/00; B01J13/00; C08K3/16; C08K5/16; C08L3/00
Domestic Patent References:
| JP2003507514A | 2003-02-25 | |||
| JP2004514734A | 2004-05-20 | |||
| JP2007513970A | 2007-05-31 | |||
| JP2005505674A | 2005-02-24 | |||
| JP2006526052A | 2006-11-16 |
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Masaru Nakajima
Ryotaro Takei
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Masaru Nakajima
Ryotaro Takei