Title:
タキサン誘導体及びこれを含む医薬
Document Type and Number:
Japanese Patent JP3942197
Kind Code:
B2
Abstract:
This invention relates to a taxane derivative represented by the following formula (1): wherein at least one of X and Y represents a group -CO-A-B in which A represents a single bond, an alkylenecarbonyl group or the like and B represents a substituted or unsubstituted piperidino group or the like, the other represents a tert-butoxycarbonyl group or the like, and Z represents a hydrogen atom or a triethylenesilyl group, and also to a drug containing the same. This compound has high solubility in water and also has excellent antitumor activities.
Inventors:
Hideaki Shimizu
Abe Atsushi
Takashi Yaegashi
Seigo Sawada
Hiroshi Nagata
Abe Atsushi
Takashi Yaegashi
Seigo Sawada
Hiroshi Nagata
Application Number:
JP50585298A
Publication Date:
July 11, 2007
Filing Date:
July 14, 1997
Export Citation:
Assignee:
Yakult Honsha Co., Ltd.
International Classes:
C07D305/14; A61K31/4523; A61K31/497; A61P35/00; C07D405/12; C07D413/12; C07D413/14
Domestic Patent References:
| JP6509107A | ||||
| JP8253465A |
Attorney, Agent or Firm:
Alga Patent Office, a patent business corporation
Miyuki Ariga
Toshio Takano
Toshio Nakajima
Hiromi Matoba
Miyuki Ariga
Toshio Takano
Toshio Nakajima
Hiromi Matoba