Title:
抗腫瘍作用を有するテルペン-キノン
Document Type and Number:
Japanese Patent JP3927232
Kind Code:
B2
Abstract:
Terpene-quinones with antitumour activity, defined from a Diels-Alder cyclocondensation reaction, thereby achieving families or series of said compounds of new structure which have cytotoxic activity against cell cultures P-388, A-549, HT-29 and MEL-28, reaching IC50 levels lower than 1 microgram per millilitre.
Inventors:
Garcia Gravaros, Maria Dolores
Golda Lisa Escobar, Marina
Miguel del Coral Santana, Jose Maria
Mahikez Buhanda, Maria del Mar
San Feliciano Martin, Arturo
Golda Lisa Escobar, Marina
Miguel del Coral Santana, Jose Maria
Mahikez Buhanda, Maria del Mar
San Feliciano Martin, Arturo
Application Number:
JP50622696A
Publication Date:
June 06, 2007
Filing Date:
August 01, 1995
Export Citation:
Assignee:
Pharma Mar, Ethea
International Classes:
C07C50/10; C07D303/12; A61K31/12; A61K31/122; A61K31/215; A61K31/335; A61K31/336; A61P35/00; C07C39/14; C07C39/225; C07C45/69; C07C46/00; C07C49/653; C07C50/14; C07C50/32; C07C61/35; C07C69/017; C07C69/157; C07C69/753; C07C69/757; C07C225/30; C07D303/16
Domestic Patent References:
| JP2292234A | ||||
| JP1186836A |
Foreign References:
| US4946869 | ||||
| US5082865 | ||||
| US5180748 |
Other References:
Fitoterapia, 1993年,64(1), p.78-80
Phytochemistry, 1994年,35(4), p.1027-1028
Phytochemistry, 1990年, 29(6), p.1955-1959
Journal of Organic Chemistry, 1969年,34(12), p.3749-3753
Tetrahedron, 1992年,48(32), p.6667-6680
Phytochemistry, 1994年,35(4), p.1027-1028
Phytochemistry, 1990年, 29(6), p.1955-1959
Journal of Organic Chemistry, 1969年,34(12), p.3749-3753
Tetrahedron, 1992年,48(32), p.6667-6680
Attorney, Agent or Firm:
Tadahiko Ito