Title:
TETRAHYDROTHIOPHENONE DERIVATIVE EFFECTIVE TO RESPIRATORY DISEASE
Document Type and Number:
Japanese Patent JPS59190989
Kind Code:
A
Abstract:
N-(2-Thenoyl)-N-(2-keto-2,3,4,5-tetrahydro-thio-phene-3-yl)amine of formula I is a valuable bronchosecretogogue, antitussive and antiinflammatory agent. It may be prepared by reacting homocysteine thiolactone hydrochloride with a reactive derivative of 2-thiofenecarboxylic acid. The compound of the invention may be formulated with conventional pharmaceutically acceptable carriers or diluents, to provide pharmaceutical composition.
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Inventors:
YASON ESU AARU ERU
Application Number:
JP5519384A
Publication Date:
October 29, 1984
Filing Date:
March 22, 1984
Export Citation:
Assignee:
YAASON ESU AARU ERU
International Classes:
A61K31/38; A61K31/381; A61P11/00; A61P11/14; C07D333/38; (IPC1-7): A61K31/38; C07D333/38
Attorney, Agent or Firm:
Sunagawa Goro