Title:
アリールヘテロアルキルアミン誘導体および一酸化窒素シンターゼのインヒビターとしてのそれらの使用
Document Type and Number:
Japanese Patent JP2005508307
Kind Code:
A
Abstract:
There are provided novel compounds of formula (I), wherein R1, R2, R3, T, U, X, Y, V and W are as defined in the specification, and pharmaceutically acceptable salts thereof, and enantiomers and racemates thereof; together with processes for their preparation, compositions containing them and their use in therapy. The compounds are inhibitors of nitric oxide synthase and are thereby particularly useful in the treatment or prophylaxis of inflammatory disease and pain.
Inventors:
David Cheshire
Steven Connolly
Antonio Mete
Steven Connolly
Antonio Mete
Application Number:
JP2003516442A
Publication Date:
March 31, 2005
Filing Date:
July 26, 2002
Export Citation:
Assignee:
ASTRAZENECA AKTIEBOLAG
International Classes:
A61K31/145; A61K31/277; A61K31/42; A61K31/44; A61K31/4402; A61K45/06; A61P1/00; A61P19/02; A61P25/00; A61P25/02; A61P25/06; A61P29/00; A61P43/00; C07C255/54; C07C257/14; C07C323/29; C07C323/62; C07D213/32; C07D213/85; C07D261/08; (IPC1-7): C07D213/85; A61K31/145; A61K31/277; A61K31/42; A61K31/44; A61K31/4402; A61P1/00; A61P19/02; A61P25/00; A61P25/06; A61P29/00; A61P43/00; C07D261/08
Attorney, Agent or Firm:
Aoyama Aoi
Mitsutaka Iwasaki
Shoji Nakajima
Kazuaki Kojima
Mitsutaka Iwasaki
Shoji Nakajima
Kazuaki Kojima