Title:
治療化合物および組成物
Document Type and Number:
Japanese Patent JP6374413
Kind Code:
B2
Abstract:
Compounds of general formula I: and compositions comprising compounds of general formula I that modulate pyruvate kinase are described herein. Also described herein are methods of using the compounds that modulate pyruvate kinase in the treatment of diseases.
Inventors:
Chanchetta, Giovanni
Popovisi-Malah, Janeta
Sarah, robert
Khao, Sheldon
Wang, Xiao Lei
Ye, Jishon
Popovisi-Malah, Janeta
Sarah, robert
Khao, Sheldon
Wang, Xiao Lei
Ye, Jishon
Application Number:
JP2015561914A
Publication Date:
August 15, 2018
Filing Date:
March 13, 2014
Export Citation:
Assignee:
Agios Pharmaceuticals, Inc.
International Classes:
C07D211/48; A61K31/445; A61K31/4525; A61K31/453; A61K31/454; A61K31/4545; A61K31/4709; A61K31/498; A61K31/517; A61K31/661; A61P7/06; A61P35/00; A61P43/00; C07D401/12; C07D401/14; C07D405/12; C07D413/12; C07D417/12; C07D417/14; C07D471/04; C07D495/04; C07F9/6558
Domestic Patent References:
| JP2012532137A | ||||
| JP2012500783A | ||||
| JP2012500834A | ||||
| JP2010522242A | ||||
| JP2006522746A | ||||
| JP2011530517A | ||||
| JP2011507910A |
Foreign References:
| WO2012151452A1 | ||||
| WO2012083246A1 | ||||
| WO2010130638A1 | ||||
| WO2006038594A1 |
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto