Title:
THERAPEUTIC GPCR TARGET IN CANCER
Document Type and Number:
Japanese Patent JP2009207497
Kind Code:
A
Abstract:
To provide new sequences for use in detection, diagnosis and treatment of cancers (especially lymphomas).
Cancer-associated (CA) polynucleotide sequences whose expression is associated with cancer are provided. CA polypeptides associated with cancer that are present on the cell surface and present new therapeutic targets against cancer are also provided. The invention relates to G-protein coupled receptor (GPCR) sequences. In addition, diagnostic compositions and methods for detecting cancer are provided. Monoclonal and polyclonal antibodies specific for the CA polypeptides are provided. Diagnostic tools and therapeutic compositions as well as methods for screening, preventing and treating cancer are also provided.
Inventors:
MORRIS DAVID W
MALANDRO MARC S
MALANDRO MARC S
Application Number:
JP2009143495A
Publication Date:
September 17, 2009
Filing Date:
June 16, 2009
Export Citation:
Assignee:
SAGRES DISCOVERY INC
International Classes:
C12N15/09; A61K31/7105; A61K31/711; A61K31/713; A61K35/76; A61K39/395; A61K45/00; A61K48/00; A61P35/00; A61P35/02; A61P43/00; C07K14/47; C07K14/705; C07K14/82; C07K16/28; C07K16/32; C12M1/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12Q1/68; G01N33/15; G01N33/50; G01N33/574; G01N33/577; A61K39/00; C12P21/08
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita
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