Title:
酸化還元活性１，４−ナフトキノンおよびその代謝産物の全合成ならびに抗マラリア薬および住血吸虫薬としての治療的使用
Document Type and Number:
Japanese Patent JP2014522378
Kind Code:
A
Abstract:
Naphthoquinones, azanaphthoquinones and benxanthones, their process of synthesis and their use as antimalarial or antischistosomal agents.
Inventors:
ダヴィオー * Sharvet, Elizabeth
Laon Francie, boss Antoine
Joan, a roll
Williams, David Lee
Cesar Rod, Elena
Laon Francie, boss Antoine
Joan, a roll
Williams, David Lee
Cesar Rod, Elena
Application Number:
JP2014501643A
Publication Date:
September 04, 2014
Filing Date:
March 29, 2012
Export Citation:
Assignee:
サントル National ドゥ ラルシェルシュ Cyanogen tee フィク
International Classes:
C07C50/32; A61K31/121; A61K31/122; A61K31/192; A61K31/216; A61K31/277; A61K31/352; A61K31/4409; A61K31/47; A61K31/495; A61K31/5375; A61P33/12; C07C46/00; C07C49/84; C07C50/24; C07C205/46; C07C255/26; C07C309/65; C07D213/50; C07D215/24; C07D295/08; C07D295/10; C07D311/78
Domestic Patent References:
| JPS6345257A | 1988-02-26 | |||
| JPH05221996A | 1993-08-31 | |||
| JPS6461440A | 1989-03-08 |
Foreign References:
| WO2009118327A1 | 2009-10-01 | |||
| US5476933A | 1995-12-19 | |||
| WO2010006153A2 | 2010-01-14 | |||
| WO2009113569A1 | 2009-09-17 |
Other References:
OHKAWA, SHIGENORI ET AL.: "Dual Inhibitors of Thromboxane A2 Synthase and 5-Lipoxygenase with Scavenging Activity of Active Oxy", JOURNAL OF MEDICINAL CHEMISTRY, vol. 34(1), JPN6015042320, 1991, pages pp. 267-276
WASKE PRASHANT A: "PHOTOACYLATIONS OF 2-SUBSTITUTED 1,4-NAPHTHOQUINONES: 以下備考", TETRAHEDRON LETTERS, vol. V47 N8, JPN5014005219, 20 February 2006 (2006-02-20), NL, pages 329 - 1332
CLAUDE COMMANDEUR ET AL.: "Study of Radical Decarboxylation Toward Functionalization of Naphthoquinones", EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, JPN6015042322, 2007, pages pp. 3045-3052
NASR, M. ET AL.: "Synthesis of Benzo-Benzothiopyranoquinolines (Pyridobenzothioxanthones) as Possible Schistosomicidal", PHARMAZIE, vol. 33(7), JPN6015042324, 1978, pages pp. 424-426
BACHMAN, G. BRYANT ET AL.: "Compounds of pharmaceutical interest from 4-methoxy-1-naphthylamine", JOURNAL OF ORGANIC CHEMISTRY, vol. 11, JPN6015042326, 1946, pages pp. 454-462
DRAKE, NATHAN L. ET AL.: "Quinolinequinones. I. Quinones and Hydroquinones Related to Pentaquine", JOURNA OF THE AMERICA CHEMICAL SOCIETY, vol. 73, JPN6015042328, 1951, pages pp. 544-550
MECKLENBURG, SUSANNE ET AL.: "Exploring synthetic avenues for the effective synthesis of selenium- and tellurium-containing mu", ORGANIC & BIOMOLECULAR CHEMISTRY, vol. 7(22), JPN7015002893, 2009, pages pp. 4753-4762
WASKE PRASHANT A: "PHOTOACYLATIONS OF 2-SUBSTITUTED 1,4-NAPHTHOQUINONES: 以下備考", TETRAHEDRON LETTERS, vol. V47 N8, JPN5014005219, 20 February 2006 (2006-02-20), NL, pages 329 - 1332
CLAUDE COMMANDEUR ET AL.: "Study of Radical Decarboxylation Toward Functionalization of Naphthoquinones", EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, JPN6015042322, 2007, pages pp. 3045-3052
NASR, M. ET AL.: "Synthesis of Benzo-Benzothiopyranoquinolines (Pyridobenzothioxanthones) as Possible Schistosomicidal", PHARMAZIE, vol. 33(7), JPN6015042324, 1978, pages pp. 424-426
BACHMAN, G. BRYANT ET AL.: "Compounds of pharmaceutical interest from 4-methoxy-1-naphthylamine", JOURNAL OF ORGANIC CHEMISTRY, vol. 11, JPN6015042326, 1946, pages pp. 454-462
DRAKE, NATHAN L. ET AL.: "Quinolinequinones. I. Quinones and Hydroquinones Related to Pentaquine", JOURNA OF THE AMERICA CHEMICAL SOCIETY, vol. 73, JPN6015042328, 1951, pages pp. 544-550
MECKLENBURG, SUSANNE ET AL.: "Exploring synthetic avenues for the effective synthesis of selenium- and tellurium-containing mu", ORGANIC & BIOMOLECULAR CHEMISTRY, vol. 7(22), JPN7015002893, 2009, pages pp. 4753-4762
Attorney, Agent or Firm:
Shintaro Nogawa
Worth Shinji
Hirosuke Kaneko
Kiyoshi Inemoto
Masami Tomita
Worth Shinji
Hirosuke Kaneko
Kiyoshi Inemoto
Masami Tomita