Title:
ポリマーの治療的使用
Document Type and Number:
Japanese Patent JP4633258
Kind Code:
B2
Abstract:
An insoluble polymer is deposited in a body cavity for instance to embolize a vein or pack an aneurysm, the polymer having pendant zwitterionic groups to improve biocompatibility. The insoluble polymer is preferably formed by an in situ gelling step in which a charged, preferably soluble, polymer having pendant zwitterionic groups is introduced in the form of a composition in which it is soluble and is gelled by being mixed with a counterionically charged soluble polymer (polyelectrolyte), to form a polyion complex. Preferably the or each soluble polymer is formed by polymerizing ethylenically unsatured monomers including a zwitterionic monomer, for instance 2-methacryloyloxyethyl-2'-trimethylammoniumethyl phosphate inner salt, an ionic monomer such as trimethylammonium alkyl(alk)acrylate or a sulphoalkyl(alk)acrylate and optionally a diluent monomer such as an alkyl(alk)acrylate.
Inventors:
Stratoford, Peter William
Court, Jane Louise
Lewis, Andrew Leonard
Court, Jane Louise
Lewis, Andrew Leonard
Application Number:
JP2000581970A
Publication Date:
February 16, 2011
Filing Date:
November 12, 1999
Export Citation:
Assignee:
Biocompatibles YuK Limited
International Classes:
A61K31/74; A61B17/12; A61F2/06; A61K31/80; A61K47/30; A61K49/04; A61P9/00; A61P9/14; C08F12/04; C08F16/14; C08F20/10; C08F22/40; C08F30/02
Domestic Patent References:
| JP7238124A | ||||
| JP6107549A |
Foreign References:
| WO1997027888A1 |
Attorney, Agent or Firm:
Patent business corporation Odashima patent office