To provide a thermoelectric generation system which dispenses with required power such as a heat medium circulation, etc., by using the shaft power making use of a steam turbine utilizing waste heat or a sealed gas turbine.

A thermoelectric generation system has a thermoelectric generator 20, which converts a part of the quantity of 9 heat that high-temperature exhaust gas 10 has into power, a heat drive source 30 which converts the whole or one part of the remaining quantity of heat of the high-temperature gas 10 into shaft power, one or plural coolers 6 which produces a cooled heat medium used for a heat exchanger(HEX 5) for the heat drive source of the thermoelectric generator 20 and the heat drive source 30, and a pump P2 which circulates a heat medium between the thermoelectric generator 20 and the heat drive source 30, and the cooler 6, and the drive force of the cooler 6 and the circulation pump P2 is obtained from the shaft power.