Title:
増殖性疾患の治療のためのチアゾール
Document Type and Number:
Japanese Patent JP5344923
Kind Code:
B2
Abstract:
The invention relates to compounds of structural formula (I): or a pharmaceutically acceptable salt, solvate, clathrate, and prodrug thereof, wherein Ra, Rb, and R2 are defined herein. These compounds inhibit tubulin polymerization and/or target vasculature and are useful for treating proliferative disorders, such as cancer.
Inventors:
Sung Li Jun
Gian Jun
Borella Christopher
Chen Show Jun
Keizo Furuya
Gian Jun
Borella Christopher
Chen Show Jun
Keizo Furuya
Application Number:
JP2008541386A
Publication Date:
November 20, 2013
Filing Date:
November 17, 2006
Export Citation:
Assignee:
Shinta Pharmaceuticals Corporation
International Classes:
C07D275/02; A61K31/425; A61P27/02; A61P35/00; A61P43/00
Foreign References:
| US5840746 | ||||
| WO2004035553A1 | ||||
| WO2005034952A2 | ||||
| WO1997003667A1 |
Other References:
Gauthier JY et al,Bioorg Med Chem Lett,1996年,Vol.6,p.87-92
Attorney, Agent or Firm:
Hatsushi Shimizu
Toshi Gobe
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Ryuichi Inoue
Masato Ozeki
Toshi Gobe
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Ryuichi Inoue
Masato Ozeki