Title:
チエノピリミドン化合物
Document Type and Number:
Japanese Patent JP5000490
Kind Code:
B2
Abstract:
The present invention relates to a compound represented by the formula:
wherein
Ar is an optionally substituted ring;
A is a spacer having a main chain of 1 to 4 atoms;
B is a bond, a C 1-10 alkylene group or an oxygen atom;
R 3 and R 5 are each independently a hydrogen atom or a substituent;
R 4 is an optionally substituted cyclic group or an optionally substituted C 1-10 alkyl group; and
R 1 and R 2 are each independently a hydrogen atom or a substituent, or
R 1 and R 2 or R 1 and B are bonded to form an optionally substituted nitrogen-containing heterocycle, or
R 1 and Ar are bonded to form an optionally substituted nitrogen-containing fused heterocycle, or a salt thereof. The thienopyrimidone compound of the present invention has a superior melanin-concentrating hormone receptor antagonistic action, and is useful as an agent for the prophylaxis or treatment of obesity and the like.
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Inventors:
Toshiki Murata
Makino Shingo
Makino Shingo
Application Number:
JP2007514869A
Publication Date:
August 15, 2012
Filing Date:
April 27, 2006
Export Citation:
Assignee:
Takeda GmbH
International Classes:
C07D495/04; A61K31/519; A61K31/55; A61P3/04; A61P43/00
Domestic Patent References:
| JP2005510487A | 2005-04-21 | |||
| JP2002241274A | 2002-08-28 | |||
| JP2002003370A | 2002-01-09 |
Foreign References:
| WO2004092181A1 | 2004-10-28 |
Attorney, Agent or Firm:
Takashima Ichi