リボヌクレオチドレダクターゼR2に向けられたアンチセンスオリゴヌクレオチドおよび癌の処置のための併用療法におけるこの使用

Title:

リボヌクレオチドレダクターゼR2に向けられたアンチセンスオリゴヌクレオチドおよび癌の処置のための併用療法におけるこの使用

Document Type and Number:

Japanese Patent JP2007520474

Kind Code:

A

Abstract:

Combination products comprising an antisense oligonucleotide against the gene encoding a mammalian ribonucleotide reductase R2 protein and one or more immunotherapeutic agents, such as cytokines, non-cytokine adjuvants, monoclonal antibodies and cancer vaccines. The combinations can further comprise one or more chemotherapeutic agents. Methods of treating cancer in a mammal using the combinations are also provided.

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Inventors:

Young, Aping H.
Light, Jim A.
Lee, Yoon

Application Number:

JP2006548057A

Publication Date:

July 26, 2007

Filing Date:

January 12, 2005

Export Citation:

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Assignee:

Gene Sense Technologies, Inc.

International Classes:

A61K48/00; A61K31/7088; A61K31/711; A61K31/7125; A61K38/19; A61K39/395; A61K45/00; A61K45/06; A61P35/00; A61P35/02; A61P35/04; A61P43/00; C12N15/11; C12N15/113; C12N15/09

Domestic Patent References:

JP2003500006A	2003-01-07
JP2000513230A	2000-10-10

Attorney, Agent or Firm:

Kiyoji Kuzuwa

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