N-[2-ヒドロキシカルバモイル-2-(ピペラジニル)エチル]ベンズアミド化合物、それらの製法及びTACE阻害剤としてのそれらの使用

Japanese Patent JP2013505215

A

The present invention relates to novel benzene-carboxamide compounds having a structure that corresponds to the general formula (I), and also to their method of synthesis and to their use in pharmaceutical compositions intended for use in human or veterinary medicine or else to their use in cosmetic compositions.

Sandrin Chambon
Laurence Clary
Marlene Supri

JP2012529266A

February 14, 2013

September 16, 2010

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Galderma Research and Development

C07D209/12; A61K31/4164; A61K31/437; A61K31/4427; A61K31/495; A61K31/496; A61K31/551; A61P1/04; A61P3/04; A61P3/10; A61P9/00; A61P9/10; A61P11/00; A61P11/06; A61P11/16; A61P17/00; A61P17/06; A61P19/02; A61P19/08; A61P21/00; A61P25/00; A61P25/02; A61P25/04; A61P25/08; A61P25/14; A61P25/16; A61P25/28; A61P27/02; A61P29/00; A61P31/00; A61P31/04; A61P31/18; A61P33/06; A61P35/00; A61P37/02; A61P37/06; A61P37/08; A61P43/00; C07B53/00; C07B57/00; C07D213/30; C07D215/14; C07D231/12; C07D233/02; C07D295/22; C07D307/80; C07D401/12; C07D471/04

JP2002535383A	2002-10-22
JP2002535383A	2002-10-22

US20040072802A1	2004-04-15
WO2008045671A1	2008-04-17
WO2002030873A1	2002-04-18
US20040072802A1	2004-04-15
WO2008045671A1	2008-04-17
WO2002030873A1	2002-04-18

JPN6014036289; Ｙｏｋｏｔａ　Ｋｏｉｃｈｉ　ｅｔ　ａｌ．: Ｅｘｐｅｒｔ　Ｏｐｉｎｉｏｎ　ｏｎ　Ｔｈｅｒａｐｅｕｔｉｃ　Ｐａｔｅｎｔｓ １５（４）, 2005, ｐ．　４２１-４３５
JPN6014036290; Ｄｕａｎ，　Ｊａｍｅｓ　Ｊ．-Ｗ　ｅｔ　ａｌ．: Ｂｉｏｏｒｇａｎｉｃ　＆　Ｍｅｄｉｃｉｎａｌ　Ｃｈｅｍｉｓｔｒｙ　Ｌｅｔｔｅｒｓ １８（１）, 2008, ｐ．　２４１-２４６
JPN6014036289; Ｙｏｋｏｔａ　Ｋｏｉｃｈｉ　ｅｔ　ａｌ．: Ｅｘｐｅｒｔ　Ｏｐｉｎｉｏｎ　ｏｎ　Ｔｈｅｒａｐｅｕｔｉｃ　Ｐａｔｅｎｔｓ １５（４）, 2005, ｐ．　４２１-４３５
JPN6014036290; Ｄｕａｎ，　Ｊａｍｅｓ　Ｊ．-Ｗ　ｅｔ　ａｌ．: Ｂｉｏｏｒｇａｎｉｃ　＆　Ｍｅｄｉｃｉｎａｌ　Ｃｈｅｍｉｓｔｒｙ　Ｌｅｔｔｅｒｓ １８（１）, 2008, ｐ．　２４１-２４６

Yasuhiko Murayama
Masatake Shiga
Takashi Watanabe
Shinya Mitsuhiro

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