Title:
時限パルス放出組成物
Document Type and Number:
Japanese Patent JP5328071
Kind Code:
B2
Abstract:
The present invention provides a timed pulse release composition comprising: a. a core composition comprising a therapeutically active agent, a swelling agent, and optionally water soluble compound(s) for inducing osmosis, and b. a coat composition comprising one or more film forming polymers, wherein upon imbibing fluid from the surrounding the core swells, and the coat ruptures to release in a pulse, the therapeutically active agent in a reliable manner at about a predetermined time wherein the reliable manner of rupture comprises rupturing of 36 tablets out of a total of 36 tablets at about the predetermined time when tested by subjecting the tablets to USP dissolution test using an aqueous media at 37±0.5oC, in a USP Type I or Type II apparatus at an rpm selected from the range of about 50 rpm to about 100 rpm.
Inventors:
Diplip Chantilly Shangubi
Nitin Balachandra Dharmadikari
Yashoradi Rupsin Zara
The Tissue Tse Canna
Nitin Balachandra Dharmadikari
Yashoradi Rupsin Zara
The Tissue Tse Canna
Application Number:
JP2002578926A
Publication Date:
October 30, 2013
Filing Date:
April 09, 2002
Export Citation:
Assignee:
Sun Pharma Advanced Research Company Limited
International Classes:
A61K9/24; A61K9/36; A61K9/50; A61K31/155; A61K31/64; A61K45/06; A61K47/02; A61K47/04; A61K47/30; A61K47/32; A61K47/34; A61K47/36; A61K47/38; A61P1/12; A61P3/10; A61P5/00; A61P5/14; A61P5/38; A61P7/02; A61P9/00; A61P11/06; A61P11/14; A61P15/00; A61P15/08; A61P15/10; A61P17/00; A61P19/10; A61P25/02; A61P25/04; A61P25/06; A61P25/08; A61P25/16; A61P25/20; A61P25/28; A61P25/30; A61P25/32; A61P27/06; A61P29/00; A61P31/04; A61P35/00; A61P37/06; A61P37/08; A61P43/00; A61K9/16
Domestic Patent References:
| JP363220A | ||||
| JP363218A | ||||
| JP2000513751A | ||||
| JP9104620A | ||||
| JP11513989A | ||||
| JP4501425A | ||||
| JP2000516637A | ||||
| JP60241871A | ||||
| JP8506092A |
Foreign References:
| WO1999018938A1 | ||||
| WO1998056364A1 |
Attorney, Agent or Firm:
Kyousei Tamura
Samejima Mutsumi
Masahiro Nitta
Kure Hidenori
Samejima Mutsumi
Masahiro Nitta
Kure Hidenori