Title:
弾性が改良された組織接着剤
Document Type and Number:
Japanese Patent JP2009542843
Kind Code:
A
Abstract:
An embodiment of the invention is a water soluble chain-extended polyamine product made by a process comprising reacting a multi-arm polyether amine with a bifunctional crosslinker of the formula: X1—R—X2. Another embodiment is a water soluble chain-extended polyamine product made by a process comprising reacting a multi-arm polyether having at least three arms and three electrophilic endgroups with a primary diamine crosslinker of the formula: NH2—R2—NH2, followed by treating of the chain-extended product so as to convert the remaining electrophilic endgroups to amine endgroups. Crosslinking of the chain-extended polyamine products with an oxidized polysaccharide provides useful tissue adhesives with modified elasticity, that provides greater compliance to underlying tissue, and improved stability in aqueous environments.
Inventors:
Henry Keith Shenoord
Garrett Dee Figary
Garrett Dee Figary
Application Number:
JP2009518185A
Publication Date:
December 03, 2009
Filing Date:
June 22, 2007
Export Citation:
Assignee:
E.I.DU PONT DE NEMOURS AND COMPANY
International Classes:
C08G65/329; A61L24/00; A61L26/00
Domestic Patent References:
| JP2008515556A | 2008-05-15 | |||
| JP2001518528A | 2001-10-16 | |||
| JP2000502380A | 2000-02-29 | |||
| JP2010511091A | 2010-04-08 | |||
| JP2005336491A | 2005-12-08 | |||
| JPH03500303A | 1991-01-24 | |||
| JP2008515556A | 2008-05-15 | |||
| JP2001518528A | 2001-10-16 | |||
| JP2000502380A | 2000-02-29 | |||
| JP2010511091A | 2010-04-08 | |||
| JP2005336491A | 2005-12-08 | |||
| JPH03500303A | 1991-01-24 |
Attorney, Agent or Firm:
Junji Yuda
Noriyuki Takebayashi
Chika Takagi
Noriyuki Takebayashi
Chika Takagi