Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
組織選択的導入遺伝子発現
Document Type and Number:
Japanese Patent JP7246359
Kind Code:
B2
Abstract:
Provided herein are compositions and methods for selective expression of a transgene. Compositions and methods for selective expression of a transgene comprise one or more human regulatory elements, which, when operably linked to a transgene, can facilitate selective expression of a transgene (for example, cell-type selective expression) in a target cell as compared to at least one or more non-target cells.

Inventors:
Tagria Terra, Stephanie
Young, Andrew
Chen, Zoo-In
Rama Morti, Cartik
Overkovler, David
Application Number:
JP2020502552A
Publication Date:
March 27, 2023
Filing Date:
April 03, 2018
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
Encoded Therapeutics, Incorporated
International Classes:
C12N15/63; A61K35/76; A61K48/00; A61P25/00; A61P25/08; A61P25/28; C12N15/09; C12N15/864; C12N15/867
Domestic Patent References:
JP2009519710A
Foreign References:
WO2012087983A1
US20140142160
US20150353917
Other References:
Axel H. Meyer et al.,In Vivo Labeling of Parvalbumin-Positive Interneurons and Analysis of Electrical Coupling in Identified Neurons,The Journal of Neuroscience,2002年,Vol.22, No.16,pp.7055-7064
NOBUAKI TAMAMAKI et al.,Green Fluorescent Protein Expression and Colocalization with Calretinin, Parvalbumin, and Somatostatin in the GAD67-GFP Knock-In Mouse,THE JOURNAL OF COMPARATIVE NEUROLOGY,2003年,Vol.467,pp.60-79
Anthony N. van den Pol and Prabhat K. Ghosh,Selective Neuronal Expression of Green Fluorescent Protein with Cytomegalovirus Promoter Reveals Entire Neuronal Arbor in Transgenic Mice,The Journal of Neuroscience,1998年,Vol.18, No.24,pp.10640-10651
Attorney, Agent or Firm:
Shusaku Yamamoto
Morishita Natsuki
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto