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Title:
組織染色およびその使用
Document Type and Number:
Japanese Patent JP7282672
Kind Code:
B2
Abstract:
Provided is a tissue staining composition containing carbon particles having a mean particle diameter less than 0.3 μm in diameter (optionally less than 0.2 μm in diameter) together with one or more agents that maintain the carbon particles in suspension (for example, an anti-settling agent and/or surfactant). In certain circumstances, the anti-settling agent may also have mucoadhesive properties. The tissue staining composition is visually dark and does not disperse rapidly when introduced into regions of tissue of interest making it ideal for marking the regions that can be visualized clearly and over prolonged periods of time via, for example, direct visualization, endoscopic or laparoscopic inspection. The invention also provides methods of making and using the tissue staining composition for marking regions of tissue of interest, for example, gastrointestinal tissue, as well as other tissues.

Inventors:
Warren, Robert Zee
Cameron, Amy A.
Tim, Mary Joe
Lee, Patrick
Application Number:
JP2019507908A
Publication Date:
May 29, 2023
Filing Date:
January 31, 2018
Export Citation:
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Assignee:
GI SUPPLY
International Classes:
G01N33/48; G01N33/483
Domestic Patent References:
JP2005521707A
JP6294081A
JP2007114129A
JP2007262062A
Foreign References:
US20020031474
US6815170
US6280702
Other References:
GI Supply,Safety Data Sheet,カタログ,2015年,GISDS003, Revision 3,[online], [令和3年10月14日検索], インターネット
INRS,Noir de carbone,ホームページ,2020年09月,[online], [令和3年10月14日検索], インターネット
Attorney, Agent or Firm:
Patent Attorney Fukami Patent Office